Extracellular Matrix Restore

Regenerative + restorative elixir | 30ml

Extracellular Matrix Restore

Regenerative + restorative elixir | 30ml

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A bioactive second skin that amplifies the impact and outcomes of in-office treatments by directing extracellular matrix (ECM) regeneration, supporting healthy skin cell activity, and modulating inflammatory responses during recovery. 

Powered by our proprietary DiamondCore® biotechnology, which:

• Enhances ECM remodeling—198% more fibroblast growth, 91% more collagen synthesis.

• Repairs damage by eradicating 80% of inflammatory Reactive Oxygen Species.

• Improves epidermal density by up to 182%.

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  • 198% increase in fibroblast growth and migration. 
  • 182% increase in epidermal thickness.
  • 163% increase in perlecan expression.
  • 108% increase in fibromodulin expression.
  • 91% increase in collagen synthesis. 
  • 79% increase in skin's own hyaluronic acid production.
  • 32% increase in keratinocyte proliferation.
  • Powered by DiamondCore® + Collagen III + Growth Factors + Peptides.
  • Accelerates visible regeneration.
  • Supports ECM renewal.
  • Improves epidermal density + structure.
  • Calms inflammation, pain, itching.
  • Prevents post-inflammatory dark spots.
  • Prevents oxidative stress + damage.
  • Anhydrous • bacteriostatic • preservative-free
  • Fragrance free • cruelty-free • vegan • gluten-free • dermatologist and medical oncologist-tested + developed

As an extension to in-office procedures, apply a generous, even layer to treated skin immediately post-treatment, and reapply as needed or as directed by your medical professional. Suitable for sensitive and post-procedure skin, including skin with a compromised barrier.

Human Recombinant Collagen III

Human Recombinant Collagen III

Human Recombinant Growth Factors

Human Recombinant Growth Factors

Signaling proteins that promote cell communication, fibroblast activation, and skin renewal. Full ingredients

Signaling Peptides

Signaling Peptides

Messengers that influence cell behavior and turnover while stimulating repair and proliferation of ECM scaffolding proteins. Full ingredients

Petrolatum, Pentaerythrityl Tetraisostearate, Caprylic/Capric Triglyceride, Undecane, Pentylene Glycol, Aluminum Starch Octenylsuccinate, Butylene Glycol, Propanediol, Passiflora Edulis (Passion Fruit) Seed Oil, Colloidal Diamond, Zinc Oxide, sr-(sh-Polypeptide-69 Dipeptide-19), Palmitoyl Hexapeptide-12, Palmitoyl Pentapeptide-4, Palmitoyl Tripeptide-1, Palmitoyl Dipeptide-10, sh-Polypeptide-10, sh-Polypeptide-1, Dipalmitoyl Hydroxyproline, Madecassoside, Centella Asiatica Extract, Ceramide NP, Panthenyl Triacetate, Palmitic Acid, Tocopherol, 4-t-butylcyclohexanol, Helianthus Annuus (Sunflower) Seed Oil, Tridecane, Triolein, Glyceryl Caprylate, Water (Aqua), Glyceryl Dioleate, Citrus Aurantium Amara (Bitter Orange) Fruit Extract, Propylene Carbonate, Stearalkonium Hectorite, Sodium Chloride, Potassium Phosphate

CRUELTY-FREE AND VEGAN

CRUELTY-FREE AND VEGAN

  • 198% increase in fibroblast growth and migration. 
  • 182% increase in epidermal thickness.
  • 163% increase in perlecan expression.
  • 108% increase in fibromodulin expression.
  • 91% increase in collagen synthesis. 
  • 79% increase in skin's own hyaluronic acid production.
  • 32% increase in keratinocyte proliferation.
  • Powered by DiamondCore® + Collagen III + Growth Factors + Peptides.
  • Accelerates visible regeneration.
  • Supports ECM renewal.
  • Improves epidermal density + structure.
  • Calms inflammation, pain, itching.
  • Prevents post-inflammatory dark spots.
  • Prevents oxidative stress + damage.
  • Anhydrous • bacteriostatic • preservative-free
  • Fragrance free • cruelty-free • vegan • gluten-free • dermatologist and medical oncologist-tested + developed

As an extension to in-office procedures, apply a generous, even layer to treated skin immediately post-treatment, and reapply as needed or as directed by your medical professional. Suitable for sensitive and post-procedure skin, including skin with a compromised barrier.

Human Recombinant Collagen III

Human Recombinant Collagen III

Human Recombinant Growth Factors

Human Recombinant Growth Factors

Signaling proteins that promote cell communication, fibroblast activation, and skin renewal. Full ingredients

Signaling Peptides

Signaling Peptides

Messengers that influence cell behavior and turnover while stimulating repair and proliferation of ECM scaffolding proteins. Full ingredients

Petrolatum, Pentaerythrityl Tetraisostearate, Caprylic/Capric Triglyceride, Undecane, Pentylene Glycol, Aluminum Starch Octenylsuccinate, Butylene Glycol, Propanediol, Passiflora Edulis (Passion Fruit) Seed Oil, Colloidal Diamond, Zinc Oxide, sr-(sh-Polypeptide-69 Dipeptide-19), Palmitoyl Hexapeptide-12, Palmitoyl Pentapeptide-4, Palmitoyl Tripeptide-1, Palmitoyl Dipeptide-10, sh-Polypeptide-10, sh-Polypeptide-1, Dipalmitoyl Hydroxyproline, Madecassoside, Centella Asiatica Extract, Ceramide NP, Panthenyl Triacetate, Palmitic Acid, Tocopherol, 4-t-butylcyclohexanol, Helianthus Annuus (Sunflower) Seed Oil, Tridecane, Triolein, Glyceryl Caprylate, Water (Aqua), Glyceryl Dioleate, Citrus Aurantium Amara (Bitter Orange) Fruit Extract, Propylene Carbonate, Stearalkonium Hectorite, Sodium Chloride, Potassium Phosphate

CRUELTY-FREE AND VEGAN

CRUELTY-FREE AND VEGAN

Clinically proven to rebuild the ECM

198%

increase in fibroblast growth and migration.

182%

increase in epidermal thickness.

91%

increase in collagen synthesis.

79%

increase in skin's own hyaluronic acid synthesis.

Corrects the full spectrum of eye aging

Dark circles 

"My puffiness and dark circles have decreased and my eyes look brighter and more awake overall."

Skin laxity

"Truly impressive firming, nothing else like it! My under eye wrinkles look smoother and overall tighter. My eyelids feel firmer and tighter too!"

ECM scaffold and signaling support

Called “baby collagen,” this form reinforces the skin's structural scaffold to maintain skin elasticity, density, and a plump, smooth texture.
Signaling proteins that activate cell communication and multi-pathway renewal signals to improve collagen organization, density, and texture over time.
Seals in hydration and strengthens the barrier to maintain ideal conditions for regeneration.
Modulates inflammatory pathways for a calmer recovery response and improved comfort.

How DiamondCore® regenerates youthful skin

DiamondCore® is scientifically proven to support healthy skin cell activity and collagen synthesis. By optimizing skin’s performance, it is better able to repair and reverse damage.

Reactive Oxygen Species are the inflammatory, damaging particles at the root of all aging. They result from sources of stress like UV radiation, air pollution, and cell dysfunction. DiamondCore® eradicates80% of ROS, preventing the cell reactions that cause aging.

DiamondCore® is scientifically proven to maximize2X the penetration and efficacy of paired age-defying active ingredients. This results in a formula that istwiceas potent.

Reviews

FAQ

Yes, Extracellular Matrix Restore is specifically designed for post-procedure skin, even the most aggressive procedures. For post-procedure recovery, apply Extracellular Matrix Restore as needed (2-4X daily) to keep impacted areas protected and moist.
Using Extracellular Matrix Restore post-procedure has been proven to improve the quality and speed of treatment outcomes by supporting higher-quality extracellular matrix architecture. Extracellular Matrix Restore optimizes post-procedure skin through stimulating fibroblast activity and shaping collagen and extracellular matrix organization during the peak regenerative window. As demonstrated in-vitro on human skin cells, DiamondCore® restores 91% of optimal collagen production and stimulates 198% better healthy skin cell growth.

Lumenis Ultrapulse CO2
* Fluence: 100 mJ
* Density: 6 (over 100% coverage, fully ablative not fractional)
* Er:YAG fluence 6.25J/cm2, 4 mm spot size

Using Extracellular Matrix Restore reduces downtime by 50%.

Apply Extracellular Matrix Restore after cleansing and layer products in the following order: Bioadaptive Stress Repair, Extracellular Matrix Restore, and Dynamic Age Defense. Like most skin treatments, it should be layered from thinnest to thickest textures for optimal absorption.

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